Comparison

Recombinant human AIF protein

Item no. NKM-ATGP2598-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSEF>LGLTP EQKQKKAALS ASEGEEVPQD KAPSHVPFLL IGGGTAAFAA ARSIRARDPG ARVLIVSEDP ELPYMRPPLS KELWFSDDPN VTKTLRFKQW NGKERSIYFQ PPSFYVSAQD LPHIENGGVA VLTGKKVVQL DVRDNMVKLN DGSQITYEKC LIATGGTPRS LSAIDRAGAE VKSRTTLFRK IGDFRSLEKI SREVKSITII
Citations Zamzami N., et al. (1996) J Exp Med. 183: 1533-1544.
Susin S A., et al. (1996) J Exp Med. 184: 1331-1341.
NCBI NP_665811
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Apoptosis-inducing factor 1 mitochondrial isoform 2 precursor,Apoptosis-inducing factor 1,mitochondrial isoform 2 precursor,AIF,CMTX4,COWCK,COXPD6,PDCD8
Similar products AIF, PDCD8, Apoptosis-inducing factor 1, CMTX4, COWCK, COXPD6, mitochondrial isoform 2 precursor, Apoptosis-inducing factor 1 mitochondrial isoform 2 precursor, ATGP2598-10ug, ATGP2598-20ug, ATGP2598-50ug, ATGP2598-100ug, ATGP2598-250ug, ATGP2598-500ug, ATGP2598-1mg, ATGP2598-10, ATGP2598-20, ATGP2598-50, ATGP2598-100, ATGP2598-250, ATGP2598-500, ATGP2598-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
58.5 kDa (537aa)
Description
Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Recombinant human AIFM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Metabolism
Domain
98-609aa
Species of Protein
Human
Manufacturer - Search Terms
AIF, Apoptosis-inducing factor 1 mitochondrial isoform 2 precursor, Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, AIF, CMTX4, COWCK, COXPD6, PDCD8, ATGP2598-10ug, ATGP2598-20ug, ATGP2598-50ug, ATGP2598-100ug, ATGP2598-250ug, ATGP2598-500ug, ATGP2598-1mg, ATGP2598-10, ATGP2598-20, ATGP2598-50, ATGP2598-100, ATGP2598-250, ATGP2598-500, ATGP2598-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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