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Recombinant human MICA protein

Recombinant human MICA protein

Item no.	NKM-ATGP3053-250ug
Manufacturer	NKMAX
Amount	250 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	MEPHSLRYNL TVLSWDGSVQ SGFLTEVHLD GQPFLRCDRQ KCRAKPQGQW AEDVLGNKTW DRETRDLTGN GKDLRMTLAH IKDQKEGLHS LQEIRVCEIH EDNSTRSSQH FYYDGELFLS QNLETEEWTM PQSSRAQTLA MNVRNFLKED AMKTKTHYHA MHADCLQELR RYLKSGVVLR RTVPPMVNVT RSEASEGNIT VTCRASGFYP WNITLSWRQD GVSLSHDTQQ WG
Citations	Strausberg, R.L, et al. (2002) Proc. Natl. Acad. Sci. u.S.A. 99 (26), 16899-16903
NCBI	AAH16929.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MHC class I polypeptide-related sequence A,MHC class I polypeptide-related sequence A,PERB11.1,truncated
Available
Manufacturer - Type	Proteins
Manufacturer - Applications	SDS-PAGE, Bioactivity
Manufacturer - Category	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	32.7 kDa (283aa) confirmed by MALDI-TOF
Description	MICA also known as MHC class I polypeptide-related sequence A. This Protein's Function seems to have no role in antigen presentation. It acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. It binding to KLRK1 leads to cell lysis. Recombinant human MICA, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol
Antigen Species	Human
Gene Category	Immunology
Domain	24-297aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured by its binding ability in a functional ELISA with Human NKG2D (CAT# ATGP3662)
Species of Protein	Human
Manufacturer - Search Terms	MICA, MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated, ATGP3053-10ug, ATGP3053-20ug, ATGP3053-50ug, ATGP3053-100ug, ATGP3053-250ug, ATGP3053-500ug, ATGP3053-1mg, ATGP3053-10, ATGP3053-20, ATGP3053-50, ATGP3053-100, ATGP3053-250, ATGP3053-500, ATGP3053-1
Manufacturer - Similar Names	MICA, MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated, ATGP3053-10ug, ATGP3053-20ug, ATGP3053-50ug, ATGP3053-100ug, ATGP3053-250ug, ATGP3053-500ug, ATGP3053-1mg, ATGP3053-10, ATGP3053-20, ATGP3053-50, ATGP3053-100, ATGP3053-250, ATGP3053-500, ATGP3053-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 ug

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Delivery expected until 12/4/2025

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