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Recombinant human Glucosylceramidase/GBA protein

Recombinant human Glucosylceramidase/GBA protein

Item no.	NKM-ATGP3145-50ug
Manufacturer	NKMAX
Amount	50 ug
Quantity options	10 ug 250 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 80% by SDS-PAGE
Sequence	ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA RYFVKFLDAY AEHKLQFWAV TA
Citations	Sorge JA., et al. (1987) Am J Hum Genet. 41:1016-1024. Salvioli R., et al. (2000) FEBS Lett. 472:17-21.
NCBI	NP_000148
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Glucosylceramidase isoform 1,GBA1,GCB,GLUC
Available
Manufacturer - Type	Proteins
Manufacturer - Category	Recombinant Protein
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	56.4 kDa (503aa)
Description	GBA, also known as glucosylceramidase isoform 1, is a lysosomal enzyme that presumably requires a signal peptide for transport across the membrane of the rough endoplasmic reticulum and glycosylation for transport into lysosomes. Gaucher disease is due to a deficiency in the activity of the enzyme glucocerebrosidase. Recombinant human GBA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Neuroscience
Domain	40-536aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein	Human
Manufacturer - Search Terms	Glucosylceramidase, GBA, Glucosylceramidase isoform 1, GBA1, GCB, GLUC, ATGP3145-10ug, ATGP3145-20ug, ATGP3145-50ug, ATGP3145-100ug, ATGP3145-250ug, ATGP3145-500ug, ATGP3145-1mg, ATGP3145-10, ATGP3145-20, ATGP3145-50, ATGP3145-100, ATGP3145-250, ATGP3145-500, ATGP3145-1
Manufacturer - Similar Names	Glucosylceramidase, GBA, Glucosylceramidase isoform 1, GBA1, GCB, GLUC, ATGP3145-10ug, ATGP3145-20ug, ATGP3145-50ug, ATGP3145-100ug, ATGP3145-250ug, ATGP3145-500ug, ATGP3145-1mg, ATGP3145-10, ATGP3145-20, ATGP3145-50, ATGP3145-100, ATGP3145-250, ATGP3145-500, ATGP3145-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/4/2025

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