Comparison

Recombinant human Legumain/Asparaginyl Endopeptidase protein

Item no. NKM-ATGP3185-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence VPIDDPEDGG KHWVVIVAGS NGWYNYRHQA DACHAYQIIH RNGIPDEQIV VMMYDDIAYS EDNPTPGIVI NRPNGTDVYQ GVPKDYTGED VTPQNFLAVL RGDAEAVKGI GSGKVLKSGP QDHVFIYFTD HGSTGILVFP NEDLHVKDLN ETIHYMYKHK MYRKMVFYIE ACESGSMMNH LPDNINVYAT TAANPRESSY ACYYDEKRST YLGDWYSVNW MEDSDVEDLT KE
Citations Dall E., et al. (2012) Proc Natl Acad Sci U S A. 110:10940-10945.
Chen JM., et al. (1996) J Biol Chem. 272:8090-8098.
NCBI NP_005597
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias LGMN,AEP,LGMN1,PRSC1
Similar products LGMN, PRSC1, Legumain, AEP, LGMN1, Asparaginyl Endopeptidase, ATGP3185-10ug, ATGP3185-20ug, ATGP3185-50ug, ATGP3185-100ug, ATGP3185-250ug, ATGP3185-500ug, ATGP3185-1mg, ATGP3185-10, ATGP3185-20, ATGP3185-50, ATGP3185-100, ATGP3185-250, ATGP3185-500, ATGP3185-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
48.4 kDa (422aa)
Description
LGMN, also known as legumain, is a cysteine endopeptidase that shows strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. It required for normal lysosomal protein degradation in renal proximal tubules. They are required for normal degradation of internalized EGFR and play a role in the regulation of cell proliferation via its role in EGFR degradation. Recombinant human LGMN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
18-433aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Legumain, Asparaginyl Endopeptidase, LGMN, AEP, LGMN1, PRSC1, ATGP3185-10ug, ATGP3185-20ug, ATGP3185-50ug, ATGP3185-100ug, ATGP3185-250ug, ATGP3185-500ug, ATGP3185-1mg, ATGP3185-10, ATGP3185-20, ATGP3185-50, ATGP3185-100, ATGP3185-250, ATGP3185-500, ATGP3185-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
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