Recombinant mouse Renin protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

REN1, also known as Renin-1, is a member of the peptidase A1 family. It is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. Androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. This protein is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Also, REN1 was found to be co localized with the lysosomal marker, beta-glucuronidase, by double-fluorescent labeling. Recombinant mouse REN1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

< 1 EU per 1ug of protein (determined by LAL method)

Renin, Ren1, Ren, Ren-A, Ren1c, Ren1d, Rn-1, Rnr, Angiotensinogenase, Kidney renin, ATGP3224-10ug, ATGP3224-20ug, ATGP3224-50ug, ATGP3224-100ug, ATGP3224-250ug, ATGP3224-500ug, ATGP3224-1mg, ATGP3224-10, ATGP3224-20, ATGP3224-50, ATGP3224-100, ATGP3224-250, ATGP3224-500, ATGP3224-1