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Recombinant mouse MESDC2 protein

Recombinant mouse MESDC2 protein

Item no.	NKM-ATGP3257-4ug
Manufacturer	NKMAX
Amount	4 ug
Quantity options	100 ug 20 ug 4 ug
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MGSADTPGEA TPPPRKKKDI RDYNDADMAR LLEQWEKDDD IEEGDLPEHK RPSAPIDFSK LDPGKPESIL KMTKKGKTLM MFVTVSGNPT EKETEEITSL WQGSLFNANY DVQRFIVGSD RAIFMLRDGS YAWEIKDFLV SQDRCAEVTL EGQMYPGKGG GSKEKNKTKP EKAKKKEGDP KPRASKEDNR AGSRREDL
Citations	Lu W., et al. (2010) Biochemistry. 49(22): 4635-43. Hoshi T., et al. (2013) FEBS Lett. 587(23): 3749-54.
NCBI	NP_075892
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	2210015O11Rik,AW537813,mesd,mKIAA0081,msd
Similar products	MESDC2, 2210015O11Rik, AW537813, mesd, mKIAA0081, msd, ATGP3257-10ug, ATGP3257-20ug, ATGP3257-50ug, ATGP3257-100ug, ATGP3257-250ug, ATGP3257-500ug, ATGP3257-1mg, ATGP3257-10, ATGP3257-20, ATGP3257-50, ATGP3257-100, ATGP3257-250, ATGP3257-500, ATGP3257-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	24.4 kDa (218aa)
Description	MESDC2 also known as LDLR chaperone MESD. This protein is specialized chaperone for low-density lipoprotein receptor-related protein 5 and LRP6. MESDC2 binds to mature LRP6 on the cell surface and blocks the binding of Wnt antagonist Dickkopf-1 to LRP6. Furthermore, MESDC2 plays an essential role in NMJ formation by promoting Lrp4 maturation. Recombinant mouse MESDC2, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Mouse
Gene Category	Signal Transduction
Domain	30-224aa
Species of Protein	Mouse
Manufacturer - Search Terms	MESDC2, 2210015O11Rik, AW537813, mesd, mKIAA0081, msd, ATGP3257-10ug, ATGP3257-20ug, ATGP3257-50ug, ATGP3257-100ug, ATGP3257-250ug, ATGP3257-500ug, ATGP3257-1mg, ATGP3257-10, ATGP3257-20, ATGP3257-50, ATGP3257-100, ATGP3257-250, ATGP3257-500, ATGP3257-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 4 ug

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Delivery expected until 7/31/2025

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