Recombinant human Aldo-keto Reductase 1C1/AKR1C1 protein

SDS-PAGE, Enzyme Activity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

AKR1C1 also known as Aldo-keto reductase family 1 member C1, is member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. Recombinant human AKR1C1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 0.1M NaCl, 20% glycerol

Metabolism

< 1 EU per 1ug of protein (determined by LAL method)

Human

Aldo-keto Reductase1C1, AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, ATGP3275-10ug, ATGP3275-20ug, ATGP3275-50ug, ATGP3275-100ug, ATGP3275-250ug, ATGP3275-500ug, ATGP3275-1mg, ATGP3275-10, ATGP3275-20, ATGP3275-50, ATGP3275-100, ATGP3275-250, ATGP3275-500, ATGP3275-1