Comparison

Recombinant mouse Legumain/Asparaginyl Endopeptidase protein

Item no. NKM-ATGP3295-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence VPVGVDDPED GGKHWVVIVA GSNGWYNYRH QADACHAYQI IHRNGIPDEQ IIVMMYDDIA NSEENPTPGV VINRPNGTDV YKGVLKDYTG EDVTPENFLA VLRGDAEAVK GKGSGKVLKS GPRDHVFIYF TDHGATGILV FPNDDLHVKD LNKTIRYMYE HKMYQKMVFY IEACESGSMM NHLPDDINVY ATTAANPKES SYACYYDEER GTYLGDWYSV NWMEDSDVED LT
Citations Shirahama-Noda K., et al. (2003) J. Biol. Chem. 278:33194-33199.
Liu C., et al. (2003) Cancer Res. 63:2957-2964.
NCBI NP_035305
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Legumain,AEP,AI746452,AU022324,Prsc1
Similar products Legumain, AEP, Asparaginyl Endopeptidase, Prsc1, AI746452, AU022324, ATGP3295-10ug, ATGP3295-20ug, ATGP3295-50ug, ATGP3295-100ug, ATGP3295-250ug, ATGP3295-500ug, ATGP3295-1mg, ATGP3295-10, ATGP3295-20, ATGP3295-50, ATGP3295-100, ATGP3295-250, ATGP3295-500, ATGP3295-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
48.6 kDa (426aa)
Description
LGMN, also known as legumain, is a lysosomal cysteine protease found in all mouse tissues, but was particularly abundant in kidney and placenta. It plays a pivotal role in the endosomal/lysosomal degradation system because the Legumain deficiency causes the accumulation of pro cathepsins B, H and L, another group of lysosomal cysteine proteases. Over expression of Legumain in tumors is significant for invasion/metastasis. Recombinant mouse LGMN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Mouse
Gene Category
Immunology
Domain
18-435aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Val18
Species of Protein
Mouse
Manufacturer - Search Terms
Legumain, Asparaginyl Endopeptidase, Legumain, AEP, AI746452, AU022324, Prsc1, ATGP3295-10ug, ATGP3295-20ug, ATGP3295-50ug, ATGP3295-100ug, ATGP3295-250ug, ATGP3295-500ug, ATGP3295-1mg, ATGP3295-10, ATGP3295-20, ATGP3295-50, ATGP3295-100, ATGP3295-250, ATGP3295-500, ATGP3295-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close