Comparison

Recombinant human CD27 Ligand/CD70 protein

Item no. NKM-ATGP3336-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>QRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRP<HH HHHH>
Citations Welten SP., et al. (2013) J. Virol. 87:6851-6865.
Polak ME., et al. (2012) J. Invest. Dermatol. 132:1636-1644.
NCBI NP_001243.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD70 antigen,CD27L,CD27LG,TNFSF7,tumor necrosis factor superfamily member 7
Similar products CD27L, CD27LG, TNFSF7, CD70 antigen, CD27 Ligand, ATGP3336-10ug, ATGP3336-20ug, ATGP3336-50ug, ATGP3336-100ug, ATGP3336-250ug, ATGP3336-500ug, ATGP3336-1mg, ATGP3336-10, ATGP3336-20, ATGP3336-50, ATGP3336-100, ATGP3336-250, ATGP3336-500, ATGP3336-1
Available
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
18.2 kDa (164aa)
Description
CD70, also known as CD70 antigen, is a transmembrane protein in the TNF receptor superfamily. It functions as a co-stimulatory molecule that supports lymphocyte activation and survival. This protein binds to the transmembrane glycoprotein CD27 ligand/CD70 which is expressed on activated B cells, activated T cells, and dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T cell activation, and thus is proliferation of co-stimulated T cells, as well as the generation of cytolytic T cells. Recombinant human CD70, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
39-193aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human CD27/TNFRSF7 (CAT# ATGP3416).
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
CD27 Ligand, TNFSF7, CD70 antigen, CD27L, CD27LG, TNFSF7, ATGP3336-10ug, ATGP3336-20ug, ATGP3336-50ug, ATGP3336-100ug, ATGP3336-250ug, ATGP3336-500ug, ATGP3336-1mg, ATGP3336-10, ATGP3336-20, ATGP3336-50, ATGP3336-100, ATGP3336-250, ATGP3336-500, ATGP3336-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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