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Recombinant human Integrin beta 2/CD18 protein

Recombinant human Integrin beta 2/CD18 protein

Item no.	NKM-ATGP3351-10ug
Manufacturer	NKMAX
Amount	10 ug
Quantity options	10 ug 250 ug 50 ug
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Cholesterol & Lipid Metabolism Aging & Neurological Disorders Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Obesity SDS-PAGE By Organ Bladder Cancer Oligodendrocyte Markers Other Lipid\Cholesterol Metabolism Modulators
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 85% by SDS-PAGE
Sequence	QECTKFKVSS CRECIESGPG CTWCQKLNFT GPGDPDSIRC DTRPQLLMRG CAADDIMDPT SLAETQEDHN GGQKQLSPQK VTLYLRPGQA AAFNVTFRRA KGYPIDLYYL MDLSYSMLDD LRNVKKLGGD LLRALNEITE SGRIGFGSFV DKTVLPFVNT HPDKLRNPCP NKEKECQPPF AFRHVLKLTN NSNQFQTEVG KQLISGNLDA PEGGLDAMMQ VAACPEEIGW RN
Citations	Law SK., et al. (1987) EMBO J. 6:915-919. Xu J., et al. (2008) Nat Immunol. 9:880-886.
NCBI	NP_000202.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ITGB2,Cell surface adhesion glycoproteins LFA-1,CR3,p150,95 subunit beta,Complement receptor C3 subunit beta,MFI7,MAC-1
Similar products	ITGB2, CD18, MFI7, Integrin beta-2, LAD, MF17, LFA-1, MAC-1, LCAMB, Integrin a L b2, ATGP3351-10ug, ATGP3351-20ug, ATGP3351-50ug, ATGP3351-100ug, ATGP3351-250ug, ATGP3351-500ug, ATGP3351-1mg, ATGP3351-10, ATGP3351-20, ATGP3351-50, ATGP3351-100, ATGP3351-250, ATGP3351-500, ATGP3351-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	75.9 kDa (686aa)
Description	ITGB2, also known as integrin beta-2, is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It may belong to an extended family of cell surface molecules including the fibronectin binding protein. Also It is a complement receptor type 3 (CR3). It triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Recombinant human ITGB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Signal Transduction
Domain	23-700aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm	Gln23
Species of Protein	Human
Manufacturer - Search Terms	Integrin a L b2, Integrin beta-2, ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, ATGP3351-10ug, ATGP3351-20ug, ATGP3351-50ug, ATGP3351-100ug, ATGP3351-250ug, ATGP3351-500ug, ATGP3351-1mg, ATGP3351-10, ATGP3351-20, ATGP3351-50, ATGP3351-100, ATGP3351-250, ATGP3351-500, ATGP3351-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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