Recombinant mouse B7-1/CD80 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Cd80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. It is the ligand for two different proteins on the T cell surface: Cd28 (for autoregulation and intercellular association) and Ctla4 (for attenuation of regulation and cellular disassociation). This protein also plays a role in induction of innate immune responses by activating NF-KB-signaling pathway in macrophages. It is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. Recombinant mouse Cd80, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Gln37

B71, CD80, T-lymphocyte activation antigen CD80, Cd80, Cd28l, Ly-53, Ly53, MIC17, TSA1, ATGP3353-10ug, ATGP3353-20ug, ATGP3353-50ug, ATGP3353-100ug, ATGP3353-250ug, ATGP3353-500ug, ATGP3353-1mg, ATGP3353-10, ATGP3353-20, ATGP3353-50, ATGP3353-100, ATGP3353-250, ATGP3353-500, ATGP3353-1