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Recombinant human u-Plasminogen Activator/Urokinase protein

Recombinant human u-Plasminogen Activator/Urokinase protein

Item no.	NKM-ATGP3383-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug 5 ug
Category	Oncology Peptides & Proteins Recombinant Proteins Cardiovascular Research Atherosclerosis By Organ Breast Cancer
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	SNELHQVPSN CDCLNGGTCV SNKYFSNIHW CNCPKKFGGQ HCEIDKSKTC YEGNGHFYRG KASTDTMGRP CLPWNSATVL QQTYHAHRSD ALQLGLGKHN YCRNPDNRRR PWCYVQVGLK PLVQECMVHD CADGKKPSSP PEELKFQCGQ KTLRPRFKII GGEFTTIENQ PWFAAIYRRH RGGSVTYVCG GSLISPCWVI SATHCFIDYP KKEDYIVYLG RSRLNSNTQG EM
Citations	Crippa MP., et al. (2007) Int J Biochem Cell Biol. 39:690-694. Kunamneni A., et al. (2008) Recent Pat Cardiovasc Drug Discov. 3:45-58. Hirayama S, et al. Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation. (FEBS Open Bio. 2022){https://pubmed.ncbi.nlm.nih.gov/35298875/}
NCBI	NP_002649.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Urokinase-type plasminogen activator,PLAU,ATF,BDPLT5,QPD,u-PA,UPA,URK,Endothelial plasminogen activator inhibitor,PAI,PAI 1,PLANH1,Plasminogen activator inhibitor 1,Plasminogen activator urinary,Plasminogen activator urokinase,Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1,Serpin E1,Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1,SERPINE1,u PA,U plasminogen activator,UPA,URK,Urokinase type plasminogen activator
Similar products	PLAU, SERPINE1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, Urokinase-type plasminogen activator, Urokinase, ATF, UPA, URK, u-PA, Plasminogen activator urinary, Plasminogen activator urokinase, u PA, U plasminogen activator, Urokinase type plasminogen activator, BDPLT5, QPD, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, u-Plasminogen Activator, PAIPAI 1, ATGP3383-10ug, ATGP3383-20ug, ATGP3383-50ug, ATGP3383-100ug, ATGP3383-250ug, ATGP3383-500ug, ATGP3383-1mg, ATGP3383-10, ATGP3383-20, ATGP3383-50, ATGP3383-100, ATGP3383-250, ATGP3383-500, ATGP3383-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	47.4 kDa (419aa)
Description	PLAU, also known as urokinase-type plasminogen activator, is a serine protease which converts plasminogen to plasmin. It is a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in complement activation, cell migration, wound healing, and generation of localized extracellular proteolysis during tissue remodeling, pro-hormone conversion, carcinogenesis and neoplasia. Recombinant human PLAU, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	21-431aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm	Ser21
Species of Protein	Human
Manufacturer - Search Terms	u-Plasminogen Activator, Urokinase, Urokinase-type plasminogen activator, PLAU, ATF, BDPLT5, QPD, u-PA, UPA, URK, Endothelial plasminogen activator inhibitor, PAIPAI 1, PLANH1, Plasminogen activator inhibitor 1, Plasminogen activator urinary, Plasminogen activator urokinase, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, Serpin E1, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, SERPINE1, u PA, U plasminogen activator, UPA, URK, Urokinase type plasminogen activator, ATGP3383-10ug, ATGP3383-20ug, ATGP3383-50ug, ATGP3383-100ug, ATGP3383-250ug, ATGP3383-500ug, ATGP3383-1mg, ATGP3383-10, ATGP3383-20, ATGP3383-50, ATGP3383-100, ATGP3383-250, ATGP3383-500, ATGP3383-1
Manufacturer - Alternative Names	Urokinase-type plasminogen activator, PLAU, ATF, BDPLT5, QPD, u-PA, UPA, URK, Endothelial plasminogen activator inhibitor, PAI, PAI 1, PLANH1, Plasminogen activator inhibitor 1, Plasminogen activator urinary, Plasminogen activator urokinase, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, Serpin E1, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, SERPINE1, u PA, U plasminogen activator, UPA, URK, Urokinase type plasminogen activator

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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