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Recombinant mouse 15-PGDH/HPGD protein

Recombinant mouse 15-PGDH/HPGD protein

Item no.	NKM-ATGP3517-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins SDS-PAGE Enzymes Prostaglandin Synthases
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH MGS>MHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK
Citations	Patel FA. et al., (2003) J Clin Endocrinol Metab. 88(6):2922-33. McKeown KJ. et al., (2003) J Clin Endocrinol Metab. 88(4):1737-41. Yan M. et al., (2004) Proc Natl Acad Sci USA. 101(50):17468-73.
NCBI	NP_032304.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	15-hydroxyprostaglandin dehydrogenase [NAD+], 15-PGDH, PGDH, PGDH1, SDR36C1, Prostaglandin dehydrogenase 1
Similar products	HPGD, Prostaglandin dehydrogenase 1, 15-PGDH, PGDH, PGDH1, SDR36C1, 15-hydroxyprostaglandin dehydrogenase [NAD+], 15 hydroxyprostaglandin dehydrogenase [NAD+], 15 PGDH, 15PGDH, AV026552, 15 Hydroxyprostaglandin dehydrogenase, 15 Hydroxyprostaglandin dehydrogenase [NAD (+)], 15-Hydroxyprostaglandin dehydrogenase, 15-Hydroxyprostaglandin dehydrogenase [NAD (+)], ATGP3517-10ug, ATGP3517-20ug, ATGP3517-50ug, ATGP3517-100ug, ATGP3517-250ug, ATGP3517-500ug, ATGP3517-1mg, ATGP3517-010, ATGP3517-020, ATGP3517-050, ATGP3517-100, ATGP3517-250, ATGP3517-500, ATGP3517-01M
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	31.6 kDa (292aa)
Description	Hpgd, also known as Hydroxyprostaglandin dehydrogenase, is a member of the short-chain dehydrogenases/reductases family. It metabolizes prostaglandins (PGs) to render them. Prostaglandins (PGs) play a crucial role in mediating parturition events, and their synthesis and metabolism are regulated by PGH synthase and 15-hydroxy-PG dehydrogenase (PGDH), respectively. Hpgd, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Recombinant mouse Hpgd protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol
Antigen Species	Mouse
Gene Category	Signal Transduction
Domain	1-269aa
Species of Protein	Mouse
Manufacturer - Search Terms	15 Hydroxyprostaglandin dehydrogenase, 15 Hydroxyprostaglandin dehydrogenase [NAD (+)], 15 hydroxyprostaglandin dehydrogenase [NAD+], 15 PGDH, 15-Hydroxyprostaglandin dehydrogenase, 15-Hydroxyprostaglandin dehydrogenase [NAD (+)], 15-hydroxyprostaglandin dehydrogenase [NAD+], 15PGDH, 15-PGDH, AV026552, HPGD, PGDH, PGDH1, Prostaglandin dehydrogenase 1, SDR36C1, ATGP3517-10ug, ATGP3517-20ug, ATGP3517-50ug, ATGP3517-100ug, ATGP3517-250ug, ATGP3517-500ug, ATGP3517-1mg, ATGP3517-010, ATGP3517-020, ATGP3517-050, ATGP3517-100, ATGP3517-250, ATGP3517-500, ATGP3517-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/3/2025