Comparison

Recombinant human 2B4/CD244 protein

Item no. NKM-ATGP3552-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADL>GKGCQGS ADHVVSISGV PLQLQPNSIQ TKVDSIAWKK LLPSQNGFHH ILKWENGSLP SNTSNDRFSF IVKNLSLLIK AAQQQDSGLY CLEVTSISGK VQTATFQVFV FDKVEKPRLQ GQGKILDRGR CQVALSCLVS RDGNVSYAWY RGSKLIQTAG NLTYLDEEVD INGTHTYTCN VSNPVSWESH TLNLTQDCQN AHQEFRFWP<L EPKSCDKTHT CPPCPAPELL
Citations Brown MH., et al. (1998) J Exp Med. 188:2083-2090.
Chuang SS., et al. (2001) J Immunol. 167:6210-6216.
NCBI NP_057466.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD244 molecule natural killer cell receptor 2B4,NAIL,NKR2B4,Nmrk,SLAMF4
Similar products SLAMF4, CD244, 2B4, NAIL, NKR2B4, Nmrk, CD244 molecule natural killer cell receptor 2B4, CD244 molecule, natural killer cell receptor 2B4, Natural killer cell receptor 2B4 isoform 1, ATGP3552-10ug, ATGP3552-20ug, ATGP3552-50ug, ATGP3552-100ug, ATGP3552-250ug, ATGP3552-500ug, ATGP3552-1mg, ATGP3552-010, ATGP3552-020, ATGP3552-050, ATGP3552-100, ATGP3552-250, ATGP3552-500, ATGP3552-01M
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
50.2 kDa (448aa)
Description
CD244, also known as natural killer cell receptor 2B4 isoform 1, is a natural killer and T cell immunoglobulin superfamily surface protein and ligand of CD48. It is a cell surface glycoprotein related to CD2 and implicated in the regulation of natural killer and T lymphocyte function. It is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. It activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness. Recombinant human CD244, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
19-224aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human CD48/SLAMF2 (CAT# ATGP3642). The ED50 range ≤ 0.1 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
SLAMF4, Nmrk, NKR2B4, Natural killer cell receptor 2B4 isoform 1, natural killer cell receptor 2B4, NAIL, CD244 molecule natural killer cell receptor 2B4, CD244 molecule, CD244, 2B4, ATGP3552-10ug, ATGP3552-20ug, ATGP3552-50ug, ATGP3552-100ug, ATGP3552-250ug, ATGP3552-500ug, ATGP3552-1mg, ATGP3552-010, ATGP3552-020, ATGP3552-050, ATGP3552-100, ATGP3552-250, ATGP3552-500, ATGP3552-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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