Comparison

Recombinant human B7-H4 protein

Item no. NKM-ATGP3607-50ug
Manufacturer NKMAX
Amount 50 ug
Quantity options 10 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>LIIGFGI SGRHSITVTT VASAGNIGED GILSCTFEPD IKLSDIVIQW LKEGVLGLVH EFKEGKDELS EQDEMFRGRT AVFADQVIVG NASLRLKNVQ LTDAGTYKCY IITSKGKGNA NLEYKTGAFS MPEVNVDYNA SSETLRCEAP RWFPQPTVVW ASQVDQGANF SEVSNTSFEL NSENVTMKVV SVLYNVTINN TYSCMIENDI AKATGDIKVT ESEIKRRSHL
Citations Zeng S., et al. (2016) Mol Biol. 50:1007-1013.
Chen X., et al. (2016) Cancer Sci. 107:944-954.
NCBI NP_078902.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias V-set domain-containing T-cell activation inhibitor 1 isoform 1,VTCN1,B7-H4,B7h.5,B7H4,B7S1,B7X,PRO1291
Available
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
26.9 kDa (244aa)
Description
VTCN1, also known as v-set domain-containing T-cell activation inhibitor 1 isoform 1, is a member of the costimulatory B7 family. It has been found to be widely expressed in many kinds of tumor tissues and to play an important part in tumor progression and poor prognosis. It serves a critical role in the negative regulation of T cell-mediated antitumor immune responses. It facilitates proliferation of esophageal squamous cell carcinoma cells through promoting interleukin-6/signal transducer and activator of transcription 3 pathway activation. Recombinant human VTCN1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cell Cycle
Domain
25-259aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
B7-H4, V-set domain-containing T-cell activation inhibitor 1 isoform 1, VTCN1, B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, ATGP3607-10ug, ATGP3607-20ug, ATGP3607-50ug, ATGP3607-100ug, ATGP3607-250ug, ATGP3607-500ug, ATGP3607-1mg, ATGP3607-10, ATGP3607-20, ATGP3607-50, ATGP3607-100, ATGP3607-250, ATGP3607-500, ATGP3607-1
Manufacturer - Similar Names
B7-H4, V-set domain-containing T-cell activation inhibitor 1 isoform 1, VTCN1, B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, ATGP3607-10ug, ATGP3607-20ug, ATGP3607-50ug, ATGP3607-100ug, ATGP3607-250ug, ATGP3607-500ug, ATGP3607-1mg, ATGP3607-10, ATGP3607-20, ATGP3607-50, ATGP3607-100, ATGP3607-250, ATGP3607-500, ATGP3607-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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