Comparison

Recombinant human PD-L1/B7-H1 protein

Item no. NKM-ATGP3631-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <ADL>FTVTVPK DLYVVEYGSN MTIECKFPVE KQLDLAALIV YWEMEDKNII QFVHGEEDLK VQHSSYRQRA RLLKDQLSLG NAALQITDVK LQDAGVYRCM ISYGGADYKR ITVKVNAPYN KINQRILVVD PVTSEHELTC QAEGYPKAEV IWTSSDHQVL SGKTTTTNSK REEKLFNVTS TLRINTTTNE IFYCTFRRLD PEENHTAELV IPELPLAHPP NER<LEPKSCD
Citations Dong H., et al, (1999) Nat. Med. 5:1365-1369.
Trabattoni D., et al, (2003) Blood 101:2514-2520.
NCBI NP_054862.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Programmed cell death 1 ligand 1 isoform,CD274,B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1
Similar products CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, B7-H, B7-H1, Programmed cell death 1 ligand 1 isoform, ATGP3631-10ug, ATGP3631-20ug, ATGP3631-50ug, ATGP3631-100ug, ATGP3631-250ug, ATGP3631-500ug, ATGP3631-1mg, ATGP3631-10, ATGP3631-20, ATGP3631-50, ATGP3631-100, ATGP3631-250, ATGP3631-500, ATGP3631-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
52.5 kDa (462aa)
Description
CD274, also known as programmed cell death 1 ligand 1 isoform, is a member of the growing B7 family of immune molecules. This protein is involved in the regulation of cellular and humoral immune responses. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells. Also, it plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development. Recombinant human CD274, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
19-238aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human PD-1 (CAT# ATGP4027). The ED50 range ≤ 0.5 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
PD-L1, B7-H1, Programmed cell death 1 ligand 1 isoform, CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, ATGP3631-10ug, ATGP3631-20ug, ATGP3631-50ug, ATGP3631-100ug, ATGP3631-250ug, ATGP3631-500ug, ATGP3631-1mg, ATGP3631-10, ATGP3631-20, ATGP3631-50, ATGP3631-100, ATGP3631-250, ATGP3631-500, ATGP3631-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

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