Recombinant human CD117/c-kit protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

KIT, also known as mast/stem cell growth factor receptor Kit isoform 1, is a cytokine receptor that is expressed not only in hematopoietic stem cells but also in other cell types. It binds to receptor tyrosine kinase type III, a stem cell factor, also called a rigid factor or c-kit ligand. When this receptor binds to stem cell factor (SCF), it forms a dimer that activates intrinsic tyrosine kinase activity, which, in turn, phosphorylates and activates signaling molecules that propagate signals in cells. This receptor protects vascular smooth muscle cells from apoptosis and helps restore cardiac function after myocardial infarction. Recombinant human KIT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Human

CD117, c-kit, Mast/stem cell growth factor receptor Kit isoform 1, KIT, C-Kit, CD117, PBT, SCFR, ATGP3665-10ug, ATGP3665-20ug, ATGP3665-50ug, ATGP3665-100ug, ATGP3665-250ug, ATGP3665-500ug, ATGP3665-1mg, ATGP3665-10, ATGP3665-20, ATGP3665-50, ATGP3665-100, ATGP3665-250, ATGP3665-500, ATGP3665-1