Comparison

Recombinant human IL-15R alpha/IL15RA protein

Item no. NKM-ATGP3672-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>ITCPPPM SVEHADIWVK SYSLYSRERY ICNSGFKRKA GTSSLTECVL NKATNVAHWT TPSLKCIRDP ALVHQRPAPP STVTTAGVTP QPESLSPSGK EPAASSPSSN NTAATTAAIV PGSQLMPSKS PSTGTTEISS HESSHGTPSQ TTAKNWELTA SASHQPPGVY PQGHSDTT<LE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV
Citations Epardaud M., et al, (2008) Cancer Res. 68:2972-2983.
Stoklasek TA., et al, (2006) J Immunol. 177:6072-6080.
NCBI NP_002180
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-15 receptor subunit alpha isoform 1,IL15RA,CD215,IL-15 receptor subunit alpha
Similar products IL15 R a, ATGP3672-10ug, ATGP3672-20ug, ATGP3672-50ug, ATGP3672-100ug, ATGP3672-250ug, ATGP3672-500ug, ATGP3672-1mg, ATGP3672-10, ATGP3672-20, ATGP3672-50, ATGP3672-100, ATGP3672-250, ATGP3672-500, ATGP3672-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
45.6 kDa (417aa)
Description
IL15RA, also known as interleukin-15 receptor subunit alpha isoform 1, is a high-affinity receptor for interleukin-15. It associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. This protein can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. IL15/IL15R alpha complexes can transmit reverse signaling that promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, and cytokine secretion by the IL 15/IL15R alpha expressing cells. Recombinant human IL15RA protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
31-205aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its ability to inhibit proliferation using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is ≤2ng/ml with Human IL-15.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
IL15 R a, ATGP3672-10ug, ATGP3672-20ug, ATGP3672-50ug, ATGP3672-100ug, ATGP3672-250ug, ATGP3672-500ug, ATGP3672-1mg, ATGP3672-10, ATGP3672-20, ATGP3672-50, ATGP3672-100, ATGP3672-250, ATGP3672-500, ATGP3672-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
available

Delivery expected until 7/31/2025 

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