Comparison

Recombinant human TRAILR2/TNFRSF10B protein

Item no. NKM-ATGP3732-50ug
Manufacturer NKMAX
Amount 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence ITQQDLAPQQ RAAPQQKRSS PSEGLCPPGH HISEDGRDCI SCKYGQDYST HWNDLLFCLR CTRCDSGEVE LSPCTTTRNT VCQCEEGTFR EEDSPEMCRK CRTGCPRGMV KVGDCTPWSD IECVHKESGT KHSGEVPAVE ETVTSSPGTP ASPCS<LEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT K
Citations Finnberg NK., et al, (2016) Cancer Res. 76:700-712.
Shin GC., et al, (2016) Autophagy. 12:2451-2466.
NCBI NP_003833
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 10B isoform 1,TNFRSF10B,CD262,Death receptor 5,DR5,KILLER,KILLER/DR5,TRAIL receptor 2,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9
Similar products TNFRSF10B, TRAIL R2, ATGP3732-10ug, ATGP3732-20ug, ATGP3732-50ug, ATGP3732-100ug, ATGP3732-250ug, ATGP3732-500ug, ATGP3732-1mg, ATGP3732-10, ATGP3732-20, ATGP3732-50, ATGP3732-100, ATGP3732-250, ATGP3732-500, ATGP3732-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
43.9 kDa (394aa)
Description
TNFRSF10B, also known as tumor necrosis factor receptor superfamily member 10B isoform 1, is a member of receptors for the cytotoxic ligand TNFSF10/TRAIL. It can be activated by tumor necrosis factor-related apoptosis inducing ligand, and transduces an apoptosis signal. This protein promotes the activation of NF-kappa-B. Defects in this protein causes of head and neck squamous cell carcinomas. Recombinant human TNFRSF10B protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
56-210aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its ability to inhibit cytotoxicity using Jurkat human acute T cell leukemia cells. The ED50 range ≤5ng/ml with Human TRAIL.
Predicted nterm
Ile56
Species of Protein
Human
Manufacturer - Search Terms
TRAIL R2, TNFRSF10B, ATGP3732-10ug, ATGP3732-20ug, ATGP3732-50ug, ATGP3732-100ug, ATGP3732-250ug, ATGP3732-500ug, ATGP3732-1mg, ATGP3732-10, ATGP3732-20, ATGP3732-50, ATGP3732-100, ATGP3732-250, ATGP3732-500, ATGP3732-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

Delivery expected until 7/31/2025 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close