Comparison

Recombinant human CD3 zeta/CD247 protein

Item no. NKM-ATGP3754-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 20 ug 4 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>RVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR<HHHH HH>
Citations Tomita K., et al. (2001) J. Biol. Chem. 276:25378-25385.
Li R., et al. (2012) Lupus. 21:75-83.
NCBI NP_932170.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TCRZ,T-cell surface glycoprotein CD3 zeta chain isoform 1,T3Z,IMD25,CD3-ZETA,CD3Z,CD3Q,CD3H,CD247
Available
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
14.1 kDa (122aa)
Description
CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.2mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 6.8) containing 50% glycerol, 1mM DTT, 1mM EDTA, 0.1M NaCl
Antigen Species
Human
Gene Category
Immunology
Domain
52-164aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10ug, ATGP3754-20ug, ATGP3754-50ug, ATGP3754-100ug, ATGP3754-250ug, ATGP3754-500ug, ATGP3754-1mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M
Manufacturer - Similar Names
TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10ug, ATGP3754-20ug, ATGP3754-50ug, ATGP3754-100ug, ATGP3754-250ug, ATGP3754-500ug, ATGP3754-1mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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