Recombinant human IL-21 protein

SDS-PAGE, Bioactivity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

IL21, also known as interleukin-21 isoform 1, is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. It has broad immunoregulatory activity and can modulate both humoral and cell-mediated responses. It is important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. It is produced by activated T cells, and it influences proliferation of T and B cells and cytolytic activity of natural killer cells. It may be a critical factor in the control of persistent viral infections. It has a potential predicating significance for survival time in patients in the development of sporadic CRC. It binds to the IL-21R and can activate Janus kinase JAK1, JAK3, STAT1, and STAT3 in EDgamma-16 cells. Recombinant human IL21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Ala

IL21, Interleukin-21 isoform 1, IL21, CVID11, IL-21, Za11, ATGP3802-10ug, ATGP3802-20ug, ATGP3802-50ug, ATGP3802-100ug, ATGP3802-250ug, ATGP3802-500ug, ATGP3802-1mg, ATGP3802-10, ATGP3802-20, ATGP3802-50, ATGP3802-100, ATGP3802-250, ATGP3802-500, ATGP3802-1