Recombinant human Glutathione S-transferase mu 1/GSTM1 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

GSTM1, also known as glutathione S-transferase Mu 1, is members of the phase ll detoxification enzyme family. This protein is cytosolic protein that belongs to the mu class of the GST superfamily. The eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Also, it acts as a hormone binding protein and plays a role in maintaining hormone homeostasis in the body. Recombinant human GSTM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 2mM DTT, 0.1mM PMSF, 40% glycerol

Signal Transduction

< 1 EU per 1ug of protein (determined by LAL method)

Human