Recombinant human CTRP5/C1qTNF5 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

CTRP5, also known as Complement C1q tumor necrosis factor-related protein 5, encodes a short-chain collagen which is strongly expressed in sub-retinal pigment epithelium (sub-RPE), ciliary epithelium and adipose tissue. CTRP5 is increased in mtDNA-depleted myocytes and that it stimulates the phosphorylation of AMP activated protein kinase. CTRP5 plays an important role in the adhesion of the retinal pigment epithelium (RPE) to the Bruch Membrane, and mutations are thought to impair the adhesion, resulting in sub-RPE deposits. Recombinant human CTRP5, fused to His-tag at N-terminals, was expressed in E. coli and purified by conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH8.5) containing 30% glycerol, 0.2M NaCl

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

CTRP5, C1qTNF5, CTRP5/C1qTNF5Complement C1q tumor necrosis factor-related protein 5, CTRP5, MFRP, ATGP3859-10ug, ATGP3859-20ug, ATGP3859-50ug, ATGP3859-100ug, ATGP3859-250ug, ATGP3859-500ug, ATGP3859-1mg, ATGP3859-10, ATGP3859-20, ATGP3859-50, ATGP3859-100, ATGP3859-250, ATGP3859-500, ATGP3859-1