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Recombinant human IL-1 alpha/IL1A protein

Recombinant human IL-1 alpha/IL1A protein

Item no.	NKM-ATGP3864-50ug
Manufacturer	NKMAX
Amount	50 ug
Quantity options	100 ug 10 ug 50 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHM>SA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA
Citations	Misener VL., et al. (2008). Neuropsychobiology. 58(2):71-80. Sarkar O., et al. (2008). Biol Reprod. 78(3):445-54.
NCBI	NP_000566
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin 1 alpha,preinterleukin 1 alpha,Hematopoietin-1,Pro-interleukin-1-alpha,IL1F1,IL-1A,IL1-ALPHA,IL1
Similar products	IL1F1, IL1 a, ATGP3864-10ug, ATGP3864-20ug, ATGP3864-50ug, ATGP3864-100ug, ATGP3864-250ug, ATGP3864-500ug, ATGP3864-1mg, ATGP3864-10, ATGP3864-20, ATGP3864-50, ATGP3864-100, ATGP3864-250, ATGP3864-500, ATGP3864-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	22.4 kDa (197aa) confirmed by MALDI-TOF
Description	IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. Recombinant human IL-1alpha was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol
Antigen Species	Human
Gene Category	Hormones & Cytokines
Domain	113-271aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 for this effect is less or equal to 0.04ng/ml.
Species of Protein	Human
Manufacturer - Search Terms	IL1 a , IL1F1, ATGP3864-10ug, ATGP3864-20ug, ATGP3864-50ug, ATGP3864-100ug, ATGP3864-250ug, ATGP3864-500ug, ATGP3864-1mg, ATGP3864-10, ATGP3864-20, ATGP3864-50, ATGP3864-100, ATGP3864-250, ATGP3864-500, ATGP3864-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 7/31/2025

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