Recombinant human Neprilysin/CD10 protein

SDS-PAGE, Enzyme Activity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Neprilysin, also known as MME, is a zinc metallopeptidase expressed at the cell surface of a variety of cells. It degrades the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. It is expressed in a wide variety of tissues and is particularly abundant in kidney. It is also a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). It is of use in hematological diagnosis since it is expressed by early B, pro-B and pre-B lymphocytes, and by lymph node germinal centers. Recombinant human neprilysin, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 0.1mM PMSF, 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Ala

Neprilysin, ATGP3907-10ug, ATGP3907-20ug, ATGP3907-50ug, ATGP3907-100ug, ATGP3907-250ug, ATGP3907-500ug, ATGP3907-1mg, ATGP3907-10, ATGP3907-20, ATGP3907-50, ATGP3907-100, ATGP3907-250, ATGP3907-500, ATGP3907-1