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Recombinant human CTLA4 protein

Recombinant human CTLA4 protein

Item no.	NKM-ATGP3914-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<ADL>KAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD<L EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN
Citations	Harper K., et al. (1991) J. Immunol. 147:1037-1044. Teft WA., et al. (2006) Annu. Rev. Immunol. 24:65-97.
NCBI	NP_005205
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152,CELIAC3,Celiac disease 3,Insulin-dependent diabetes mellitus 12,IDDM12,CD,GSE
Available
Manufacturer - Type	Proteins
Manufacturer - Applications	SDS-PAGE, Bioactivity
Manufacturer - Category	Recombinant Protein
Manufacturer - Conjugate / Tag	hIgG-His-Tag
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	40.8 kDa (368aa)
Description	CTLA-4, also known as cytotoxic T-lymphocyte protein 4, is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. Recombinant human CTLA-4, fused to hIgG His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Immunology
Domain	36-161aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	The activity is determined by the IL-2 ELISA in a using Jurkat human acute T cell leukemia cells. The ED50 range ≤150ng/ml with Human B7 1/CD80.
Additional Comment Only	ATGP3364 has been replaced with a catalog number ATGP3914.
Predicted nterm	Ala
Species of Protein	Human
Manufacturer - Search Terms	Cytotoxic T lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA 4, CTLA4, CTLA-4, CD 152, CD152, CELIAC3, CELIAC 3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, Insulin dependent diabetes mellitus 12, IDDM 12, IDDM12, CD, GSE, ATGP3914-10ug, ATGP3914-20ug, ATGP3914-50ug, ATGP3914-100ug, ATGP3914-250ug, ATGP3914-500ug, ATGP3914-1mg, ATGP3914-010, ATGP3914-020, ATGP3914-050, ATGP3914-100, ATGP3914-250, ATGP3914-500, ATGP3914-01M, ATGP3364
Manufacturer - Similar Names	Cytotoxic T lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA 4, CTLA4, CTLA-4, CD 152, CD152, CELIAC3, CELIAC 3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, Insulin dependent diabetes mellitus 12, IDDM 12, IDDM12, CD, GSE, ATGP3914-10ug, ATGP3914-20ug, ATGP3914-50ug, ATGP3914-100ug, ATGP3914-250ug, ATGP3914-500ug, ATGP3914-1mg, ATGP3914-010, ATGP3914-020, ATGP3914-050, ATGP3914-100, ATGP3914-250, ATGP3914-500, ATGP3914-01M, ATGP3364

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 12/4/2025

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