Recombinant human RAGE/AGER protein

Recombinant Protein

hIgG-His-Tag

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

RAGE, also known as advanced glycosylation end product-specific receptor isoform 1, is a member of the immunoglobulin super-family transmembrane proteins. It mediates interactions of advanced glycosylation end products (AGE). AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. This protein contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. Recombinant human RAGE, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

< 1 EU per 1ug of protein (determined by LAL method)

Ala

RAGE, ATGP3923-10ug, ATGP3923-20ug, ATGP3923-50ug, ATGP3923-100ug, ATGP3923-250ug, ATGP3923-500ug, ATGP3923-1mg, ATGP3923-10, ATGP3923-20, ATGP3923-50, ATGP3923-100, ATGP3923-250, ATGP3923-500, ATGP3923-1