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Recombinant human BMP-2 protein

Recombinant human BMP-2 protein

Item no.	NKM-ATGP3940-10ug
Manufacturer	NKMAX
Amount	10 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 90% by SDS-PAGE
Sequence	MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Citations	Chen D., et al. (2004). Growth factors. 22(4):233-41 Schliephake H., et al. (2005). Clin Oral Implants Res. 17(6):666-72 Tanaka M, et al. Physico-Chemical, In Vitro, and In Vivo Evaluation of a 3D Unidirectional Porous Hydroxyapatite Scaffold for Bone Regeneration. (Materials (Basel). 2017){https://pubmed.ncbi.nlm.nih.gov/28772390/} Tanaka M, et al. In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration. (Nanomaterials (Basel). 2017){https://pubmed.ncbi.nlm.nih.gov/28336879/} Qi S, et al. Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells. (Small. 2019){https://pubmed.ncbi.nlm.nih.gov/30488562/}
NCBI	NP_001191
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Bone morphogenetic protein 2,BMP-2A
Similar products	BMP2, Bone morphogenetic protein 2, BMP-2A, ATGP3940-10ug, ATGP3940-20ug, ATGP3940-50ug, ATGP3940-100ug, ATGP3940-250ug, ATGP3940-500ug, ATGP3940-1mg, ATGP3940-10, ATGP3940-20, ATGP3940-50, ATGP3940-100, ATGP3940-250, ATGP3940-500, ATGP3940-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	13 kDa (115aa)
Description	BMP-2, also known as Bone morphogenetic protein 2, is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP2 was expressed in E. coli and purified by conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 10mM Sodium acetate (pH 3.5)
Antigen Species	Human
Gene Category	Signal Transduction
Domain	283-396aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is ≤ 100 ng/ml.
Species of Protein	Human
Manufacturer - Search Terms	BMP2, Bone morphogenetic protein 2, BMP-2A, ATGP3940-10ug, ATGP3940-20ug, ATGP3940-50ug, ATGP3940-100ug, ATGP3940-250ug, ATGP3940-500ug, ATGP3940-1mg, ATGP3940-10, ATGP3940-20, ATGP3940-50, ATGP3940-100, ATGP3940-250, ATGP3940-500, ATGP3940-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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