Recombinant human SHP-2/PTPN11 protein

Proteins

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

SHP-2, also known as, tyrosine-protein phospatase non-receptor type 11(PTPN11), is a member of the protein tyrosine phosphatase (PTP) family containing two Src homology 2 domains. This protein dephosphorylates tyrosine residues in proteins. It plays a stimulatory role in activation of the Erk/MAP kinase pathway by receptor tyrosine kinase signaling. Mutations in this protein are a cause of Noonan syndrome as well as acute myeloid leukemia. Recombinant human SHP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.

Signal Transduction, Enzymes & Proteases, Epigenetics and Nuclear Signaling

< 1 EU per 1ug of protein (determined by LAL method)

Ala

ATGP3943-10ug, ATGP3943-20ug, ATGP3943-50ug, ATGP3943-100ug, ATGP3943-250ug, ATGP3943-500ug, ATGP3943-1mg, ATGP3943-10, ATGP3943-20, ATGP3943-50, ATGP3943-100, ATGP3943-250, ATGP3943-500, ATGP3943-1