Comparison

Recombinant Human ACE Protein

Item no. NKM-ATGP3944-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence LDPGLQPGNF SADEAGAQLF AQSYNSSAEQ VLFQSVAASW AHDTNITAEN ARRQEEAALL SQEFAEAWGQ KAKELYEPIW QNFTDPQLRR IIGAVRTLGS ANLPLAKRQQ YNALLSNMSR IYSTAKVCLP NKTATCWSLD PDLTNILASS RSYAMLLFAW EGWHNAAGIP LKPLYEDFTA LSNEAYKQDG FTDTGAYWRS WYNSPTFEDD LEHLYQQLEP LYLNLHAFVR RA
Citations Amati E., et al, (2018) Stem Cell Res Ther. 9:10.
Metzger R., et al, (2000) Atherosclerosis. 150:21-31.
NCBI NP_000780
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Angiotensin-coverting enzyme,Dipeptidyl carboxypeptidase I,Kininase II,ACE1,CD143,DCP,DCP1
Similar products ATGP3944-10ug, ATGP3944-20ug, ATGP3944-50ug, ATGP3944-100ug, ATGP3944-250ug, ATGP3944-500ug, ATGP3944-1mg, ATGP3944-10, ATGP3944-20, ATGP3944-50, ATGP3944-100, ATGP3944-250, ATGP3944-500, ATGP3944-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
142kDa(1235aa)
Description
ACE, also known as peptidyl-dipetidase A, is a zinc metallopeptidase important for blood pressure control and water and salt metabolism. it converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. It's able to inactivate bradykinin, a potent vasodilator. It has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Recombinant human ACE/CD143, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
30-1256aa
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 1, 000 pmol/min/mg, and is defined as the amount of enzyme that cleaves 1pmol of Mca-RPPGFSAFK(Dnp)-OH per minute at 25C.
Predicted nterm
Leu 30
Species of Protein
Human
Manufacturer - Search Terms
, ATGP3944-10ug, ATGP3944-20ug, ATGP3944-50ug, ATGP3944-100ug, ATGP3944-250ug, ATGP3944-500ug, ATGP3944-1mg, ATGP3944-10, ATGP3944-20, ATGP3944-50, ATGP3944-100, ATGP3944-250, ATGP3944-500, ATGP3944-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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