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Recombinant Human IFN-alpha/beta R2/IFNAR2 protein

Recombinant Human IFN-alpha/beta R2/IFNAR2 protein

Item no.	NKM-ATGP3952-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	ISYDSPDYTD ESCTFKISLR NFRSILSWEL KNHSIVPTHY TLLYTIMSKP EDLKVVKNCA NTTRSFCDLT DEWRSTHEAY VTVLEGFSGN TTLFSCSHNF WLAIDMSFEP PEFEIVGFTN HINVMVKFPS IVEEELQFDL SLVIEEQSEG IVKKHKPEIK GNMSGNFTYI IDKLIPNTNY CVSVYLEHSD EQAVIKSPLK CTLLPPGQES ESAESAK<LEP KSCDKTHTCP P
Citations	Grazziola C, et al, (2005) Int J Oncol 26:129-140. Ortiz A, et al, (2019) Cancer Cell 35:33-45.
NCBI	NP_997468
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interferon alpha/beta receptor 2, IFNAR2, IFN-alpha binding protein, Interferon alpha binding protein, Type I interferon receptor 2, interferon alpha/beta receptor 2 isoform a, IFN-R-2, IFNABR, IFNARB, IFN-alpha-REC, IFN-R, IMD45
Similar products	ATGP3952-10ug, ATGP3952-20ug, ATGP3952-50ug, ATGP3952-100ug, ATGP3952-250ug, ATGP3952-500ug, ATGP3952-1mg, ATGP3952-10, ATGP3952-20, ATGP3952-50, ATGP3952-100, ATGP3952-250, ATGP3952-500, ATGP3952-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag	hIgG-His-Tag
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	51.7kDa (456aa)
Description	IFN-alpha/beta R2, also known as IFNAR2, is a member of the class II cytokine receptor family. This protein is the principal ligand binding subunit of the receptor. Ligand bindnig is stabilized by the subsequent association with IFNAR1 and forms the signaling compelx recptor. It also plays the role in STAT1, STAT2, and STAT3 activation. Recombinant human IFN-alpha/beta R2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by Absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Immunology, Hormones & Cytokines
Domain	27-243aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured by its binding ability in a functional ELISA with Human IFN-alpha 2 (CAT# IFN0502) in the presence of Human IFN-alpha/beta R1 (CAT# ATGP3894). The ED50 range ≤ 500 ng/ml.
Predicted nterm	Ile
Species of Protein	Human
Manufacturer - Search Terms	, ATGP3952-10ug, ATGP3952-20ug, ATGP3952-50ug, ATGP3952-100ug, ATGP3952-250ug, ATGP3952-500ug, ATGP3952-1mg, ATGP3952-10, ATGP3952-20, ATGP3952-50, ATGP3952-100, ATGP3952-250, ATGP3952-500, ATGP3952-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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