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Recombinant canine IL-1 beta/IL1B protein

Recombinant canine IL-1 beta/IL1B protein

Item no.	NKM-ATGP3956-10ug
Manufacturer	NKMAX
Amount	10 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Dog (Canine, Canis lupus familiaris)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MAAMQSVDCK LQDISHKYLV LSNSYELRAL HLNGENVNKQ VVFHMSFVHG DESNNKIPVV LGIKQKNLYL SCVMKDGKPT LQLEKVDPKV YPKRKMEKRF VFNKIEIKNT VEFESSQYPN WYISTSQVEG MPVFLGNTRG GQDITDFTME FSS
Citations	Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629 Curr Pharm Des. (2017), 23(32):4893-4905.
NCBI	NP_001033060.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-1 beta,IL-1 beta
Similar products	IL-1beta, IL-1, IL-1b, IL1F2, Catabolin, IL 1 beta, IL1b, IL1-beta, IL1, IL-1-beta, Interleukin 1, IL 1, Interleukin 1 beta, IL 1beta, IL1 beta, IL1 b, beta proprotein, IL 1 b, IL 1b, Interleukin 1 b, Interleukin 1b, Interleukin 1beta, ATGP3956-10ug, ATGP3956-20ug, ATGP3956-50ug, ATGP3956-100ug, ATGP3956-250ug, ATGP3956-500ug, ATGP3956-1mg, ATGP3956-010, ATGP3956-020, ATGP3956-050, ATGP3956-100, ATGP3956-250, ATGP3956-500, ATGP3956-01M
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	17.5 kDa (153aa) confirmed by MALDI-TOF
Description	Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant canine IL-1beta was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species	Canine
Gene Category	Hormones & Cytokines
Domain	114-265aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 5pg/ml.
Species of Protein	Canine
Manufacturer - Search Terms	beta proprotein, Catabolin, IL 1, IL 1 b, IL 1b, IL 1beta, IL 1 beta, IL1, IL-1, IL1 b, IL1 beta, IL1b, IL-1b, IL1-beta, IL-1beta, IL-1-beta, IL1F2, Interleukin 1, Interleukin 1 b, Interleukin 1 beta, Interleukin 1b, Interleukin 1beta, ATGP3956-10ug, ATGP3956-20ug, ATGP3956-50ug, ATGP3956-100ug, ATGP3956-250ug, ATGP3956-500ug, ATGP3956-1mg, ATGP3956-010, ATGP3956-020, ATGP3956-050, ATGP3956-100, ATGP3956-250, ATGP3956-500, ATGP3956-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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