Recombinant mouse LIFR alpha/LIFR Protein

SDS-PAGE, Bioactivity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

LIFR alpha, also known as CD118, is a member of the Interleukin-6 receptor family. Members of this family mediate the biological effects of Cardiotrophin-1, CLC, CNTF, IL-6, IL-11, IL-27, and Oncostatin M. The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR alpha has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway. LIFR alpha is down regulated in a number of breast carcinomas and may serve a prognostic tool. Recombinant mouse LIFR alpha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Leu

, ATGP3958-10ug, ATGP3958-20ug, ATGP3958-50ug, ATGP3958-100ug, ATGP3958-250ug, ATGP3958-500ug, ATGP3958-1mg, ATGP3958-10, ATGP3958-20, ATGP3958-50, ATGP3958-100, ATGP3958-250, ATGP3958-500, ATGP3958-1