Recombinant human Thrombopoietin protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Thrombopoietin, also known as megakaryocyte growth and development factor (MGDF), is a member of EPO/TPO family. It is produced in the liver by both parenchymal cells and sinusoidal endothelial cells, as well as in the kidney by proximal convoluted tubule cells. It acts as a key regulator of megakaryocytopoiesis and thrombopoiesis that leads to platelet production. Also, this protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Thrombopoietin, like EPO, plays a role in brain development. It promotes apoptosis of newly generated neurons, an effect counteracted by EPO and neurotrophins. Recombinant human Thrombopoietin fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

< 1 EU per 1ug of protein (determined by LAL method)

Asp

, ATGP3970-10ug, ATGP3970-20ug, ATGP3970-50ug, ATGP3970-100ug, ATGP3970-250ug, ATGP3970-500ug, ATGP3970-1mg, ATGP3970-10, ATGP3970-20, ATGP3970-50, ATGP3970-100, ATGP3970-250, ATGP3970-500, ATGP3970-1