Comparison

Recombinant mouse sFRP-2/SFRP2 protein

Item no. NKM-ATGP3973-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>LFLFGQP DFSYKRSNCK PIPANLQLCH GIEYQNMRLP NLLGHETMKE VLEQAGAWIP LVMKQCHPDT KKFLCSLFAP VCLDDLDETI QPCHSLCVQV KDRCAPVMSA FGFPWPDMLE CDRFPQDNDL CIPLASSDHL LPATEEAPKV CEACKTKNED DNDIMETLCK NDFALKIKVK EITYINRDTK IILETKSKTI YKLNGVSERD LKKSVLWLKD SLQCTCEEMN
Citations Alfaro, M.P. et al. (2010) J. Biol. Chem. 285:35645-35653
He, W. et al. (2010) Proc. Natl. Acad. Sci. 107:21110-21115
NCBI NP_033170.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias sFRP-2,sFRP2,Secreted frizzled-related protein 2,Secreted apoptosis-related protein 1,SDF-5,Sdf5,sdf,SARP-1,SARP1,Protein SDF5,FRP-2secreted apoptosis related protein 1,AI851596
Similar products ATGP3973-10ug, ATGP3973-20ug, ATGP3973-50ug, ATGP3973-100ug, ATGP3973-250ug, ATGP3973-500ug, ATGP3973-1mg, ATGP3973-10, ATGP3973-20, ATGP3973-50, ATGP3973-100, ATGP3973-250, ATGP3973-500, ATGP3973-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
32.1kDa (280aa)
Description
sFRP-2, also known as Secreted apoptosis-related protein 1, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. sFRP-2 can exert either positive or negative effects on Wnt signaling. At physiological concentrations, it also inhibits BMP-induced effects. It plays a variety of roles during tissue morphogenesis including inhibition of the planar cell polarity pathway and myoblast and osteoblast differentiation. It is also expressed in multiple myeloma and glioma in which it promotes tumorigenicity. Recombinant mouse sFRP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
Antigen Species
Mouse
Gene Category
Signal Transduction
Domain
25-295aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Mouse
Manufacturer - Search Terms
, ATGP3973-10ug, ATGP3973-20ug, ATGP3973-50ug, ATGP3973-100ug, ATGP3973-250ug, ATGP3973-500ug, ATGP3973-1mg, ATGP3973-10, ATGP3973-20, ATGP3973-50, ATGP3973-100, ATGP3973-250, ATGP3973-500, ATGP3973-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
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