Comparison

Recombinant human FOLR2 protein

Item no. NKM-ATGP3987-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence QDRTDLLNVC MDAKHHKTKP GPEDKLHDQC SPWKKNACCT ASTSQELHKD TSRLYNFNWD HCGKMEPACK RHFIQDTCLY ECSPNLGPWI QQVNQSWRKE RFLDVPLCKE DCQRWWEDCH TSHTCKSNWH RGWDWTSGVN KCPAGALCRT FESYFPTPAA LCEGLWSHSY KVSNYSRGSG RCIQMWFDSA QGNPNEEVAR FYAAAMHVN<H HHHHH>
Citations Ross, J.F. et al.,1994, Cancer 73:2432.
Joost W van der Heijden J.W. et al., 2009, Arthritis Rheum. 60:12-21.
NCBI NP_000794.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Folate receptor beta,FR-beta,Folate receptor 2,Folate receptor,fetal/placental,Placental folate-binding protein,FBP,FBP Protein,BETA-HFR Protein,FBP/PL-1 Protein,FR-BETA Protein,FR-P3 Protein,FRbeta,FR-BETA,FBP/PL-1,BETA-HFR
Similar products ATGP3987-10ug, ATGP3987-20ug, ATGP3987-50ug, ATGP3987-100ug, ATGP3987-250ug, ATGP3987-500ug, ATGP3987-1mg, ATGP3987-10, ATGP3987-20, ATGP3987-50, ATGP3987-100, ATGP3987-250, ATGP3987-500, ATGP3987-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.1 kDa (215aa)
Description
FOLR2, also known as Folate receptor beta, is a member of the folate receptor (FLOR) family. Members of this gene family have a high affinity for folate and folic acid analogs at neutral pH. And they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. It was originally thought to exist only in placenta, but is also expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. FOLR2 is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma. Recombinant human FOLR2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction, Metabolism
Domain
22-230aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Folic Acid-BSA. The ED50 range ≤ 5 ug/ml.
Predicted nterm
Gln 22
Species of Protein
Human
Manufacturer - Search Terms
, ATGP3987-10ug, ATGP3987-20ug, ATGP3987-50ug, ATGP3987-100ug, ATGP3987-250ug, ATGP3987-500ug, ATGP3987-1mg, ATGP3987-10, ATGP3987-20, ATGP3987-50, ATGP3987-100, ATGP3987-250, ATGP3987-500, ATGP3987-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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