Comparison

Recombinant human DR3/TNFRSF25 protein

Item no. NKM-ATGP4017-50ug
Manufacturer NKMAX
Amount 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>QGGTRSP RCDCAGDFHK KIGLFCCRGC PAGHYLKAPC TEPCGNSTCL VCPQDTFLAW ENHHNSECAR CQACDEQASQ VALENCSAVA DTRCGCKPGW FVECQVSQCV SSSPFYCQPC LDCGALHRHT RLLCSRRDTD CGTCLPGFYE HGDGCVSCPT STLGSCPERC AAVCGWRQ<LE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV
Citations Slebioda TJ., et al. (2011) Eur J Immunol. 41:2606-2611.
Fang L., et al. (2008) J Exp Medl. 205:1037-1048.
NCBI NP_003781.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 25,Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,LARD,Protein WSL,Protein WSL-1,APO3,DDR3,DR3,TNFRSF12,WSL,WSL1,TR3
Similar products ATGP3375, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
46.1kDa (417aa)
Description
TNFRSF25, also known as Tumor necrosis factor receptor superfamily member 25, is a member of the TNF receptor superfamily that binds to the TNF-like protein TL1A. TNFRSF25 signals are required to exert T helper cell 2 effector function in Th2-polarized CD4 cells and co-stimulate interleukin-13 production by glycosphingolipidactivated NKT cells. Its axis is a novel immune pathway that participates in the pathogenesis of a variety of autoimmune rheumatic diseases. These molecules may be promising therapeutic targets for inflammatory arthritis. Recombinant human TNFRSF25, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
25-199aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human TL1A/TNFSF15 (CAT# ATGP1049). The ED50 range ≤ 5 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
ATGP3375, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1
Manufacturer - Alternative Names
Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, TR3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

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