Recombinant canine IL-17A protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

IL-17A, also known as CTLA8, is a member of the IL-17 family of cytokines. This family demonstrate a structural motif termed a cysteine knot that also characterizes a large superfamily of growth factors. The IL-17 family of cytokines includes six members, IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F. IL-17A main funcion is stimulates production of IL-6, prostaglandin E and nitric oxide. And other inflammatory cytokines(TNF-alpha, IL-1 beta and IFN -gamma) leads to up-regulation of gene expression and progression and amplification of local inflammation. In addition, it serves induction of co-stimulatory molecules such as ICAM-1 and other cytokines, thereby supporting T cell activation. IL-17 expression has been associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. Recombinant canine IL-17A, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol.

Immunology, Hormones & Cytokines

< 1 EU per 1ug of protein (determined by LAL method)

Phe 29

ATGP4068-10ug, ATGP4068-20ug, ATGP4068-50ug, ATGP4068-100ug, ATGP4068-250ug, ATGP4068-500ug, ATGP4068-1mg, ATGP4068-10, ATGP4068-20, ATGP4068-50, ATGP4068-100, ATGP4068-250, ATGP4068-500, ATGP4068-1