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Recombinant human Crystallin alpha A/CRYAA protein

Recombinant human Crystallin alpha A/CRYAA protein

Item no.	NKM-CRA3001-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 1 mg 20 ug
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins SDS-PAGE Neurodegeneration Markers
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 90% by SDS-PAGE
Sequence	MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS
Citations	Hasan, A., et al.(2002) Biochemistry 41(52) 15876-15882 Bera,S., et al(2002) Biochemistry 41(41) 12421-12426 Reddy, G.B., et al(2002) FEBS lett. 522(1-3) 59-64 Andley, u.P., et al(2002) J.Biol.Chem.277(12) 10178-10186 Fan Q, et al. Identification of proteins that interact with alpha A-crystallin using a human proteome microarray. (Mol Vis. 2014){https://pubmed.ncbi.nlm.nih.gov/24453475/}
NCBI	NP_000385.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Acry-1,Alpha crystallin A chain,CRYA1,CRYAA,Crystallin alpha 1,Crystallin alpha A,Heat shock protein beta 4,HSPB 4,HspB4,Zonular Central Nuclear Cataract
Similar products	CRYAA, CRYA1, Alpha-crystallin A chain, Heat shock protein beta-4, Alpha crystallin A chain, CRYA 1, Crystallin alpha A, Heat shock protein beta 4, HSPB 4, HspB4, Zonular Central Nuclear Cataract, a A Crystallin, Acry-1, Crystallin Alpha 1, CRA3001-10ug, CRA3001-20ug, CRA3001-50ug, CRA3001-100ug, CRA3001-250ug, CRA3001-500ug, CRA3001-1mg, CRA3001-010, CRA3001-020, CRA3001-050, CRA3001-100, CRA3001-250, CRA3001-500, CRA3001-01M
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	19.9 kDa (173aa)
Description	Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 50mM NaCl, 1mM EDTA
Antigen Species	Human
Gene Category	Heat Shock Proteins
Domain	1-173aa
Species of Protein	Human
Manufacturer - Search Terms	a A Crystallin, Acry-1, Alpha crystallin A chain, Alpha-crystallin A chain, CRYA 1, CRYA1, CRYAA, Crystallin Alpha 1, Crystallin alpha A, Heat shock protein beta 4, Heat shock protein beta-4, HSPB 4, HspB4, Zonular Central Nuclear Cataract, CRA3001-10ug, CRA3001-20ug, CRA3001-50ug, CRA3001-100ug, CRA3001-250ug, CRA3001-500ug, CRA3001-1mg, CRA3001-010, CRA3001-020, CRA3001-050, CRA3001-100, CRA3001-250, CRA3001-500, CRA3001-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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