Recombinant human Desert Hedgehog/Dhh N-terminus protein

Proteins

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

DHH belongs to the hedgehog family. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N- terminal domain is the active species in both local and long-range signaling, whereas the C-terminal domain has no signaling activity. This protein is produced by Sertoli cells and may be involved in both male gonadal differentiation and perineurial development. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. Recombinant DHH protein was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM MES buffer (pH 5.5) containing 0.5mM DTT, 20% glycerol

Signal Transduction

< 1 EU per 1ug of protein (determined by LAL method)

Desert Hedgehog, Dhh N-terminus, desert hedgehog preproprotein, Drosophila, HHG-3, MGC35145, Desert hedgehog protein N-product, DHH, desert hedgehog preproprotein Desert hedgehog, Desert hedgehog (Drosophila) homolog, Desert hedgehog homolog (Drosophila), Desert hedgehog protein precursor., DHH0901-10ug, DHH0901-20ug, DHH0901-50ug, DHH0901-100ug, DHH0901-250ug, DHH0901-500ug, DHH0901-1mg, DHH0901-10, DHH0901-20, DHH0901-50, DHH0901-100, DHH0901-250, DHH0901-500, DHH0901-1