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Recombinant human Growth Hormone 1/GH1, 20kDa variant protein

Recombinant human Growth Hormone 1/GH1, 20kDa variant protein

Item no.	NKM-GRH3002-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Metabolism Diabetes Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF
Citations	Frigeri, et al (1979) Biochem Biophys Res Commun. 14:778-82 Adelman, et al (1983) DNA. 2; 183-93 Tsushima, et al (2000) Endocr J. 47; S17-21 Horan, M.,et al(2003) Hum. Mutat. 21(4), 408-423 Zhang H, et al. Facile detection of proteins on a solid-phase membrane by direct binding of dextran-based luminol-biotin chemiluminescent polymer. (Talanta. 2009){https://pubmed.ncbi.nlm.nih.gov/19576433/} Jung J, et al. Production and engineering of nanobody-based quenchbody sensors for detecting recombinant human growth hormone and its isoforms. (Drug Test Anal. 2023){https://pubmed.ncbi.nlm.nih.gov/37667448/}
NCBI	NP_072053.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Somatotropin isoform 2,20kDa Growth Hormone,GH,GH1,GHN,GH-N,Growth hormone,Growth hormone 1,hGH-N,Pituitary growth hormone,Somatotropin
Similar products	GH, GH1, Growth Hormone, Somatotropin, GH-N, Pituitary growth hormone, Growth hormone 1, GHN, hGH-N, GH 1, GRH3002-10ug, GRH3002-20ug, GRH3002-50ug, GRH3002-100ug, GRH3002-250ug, GRH3002-500ug, GRH3002-1mg, GRH3002-010, GRH3002-020, GRH3002-050, GRH3002-100, GRH3002-250, GRH3002-500, GRH3002-01M
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	20 kDa (177aa) confirmed by MALDI-TOF
Description	The 20KDa variant form of human growth hormone (20KDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22K, 191 amino acid) by the deletion of amino acid residues 32-46. The physiological role of 20K hGH remains to be determined partly but it regards the main function as stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. Recombinant 20KDa human growth hormone was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Hormones & Cytokines
Domain	27-202aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤1ng/ml.
Species of Protein	Human
Manufacturer - Search Terms	GH, GH 1, GH1, GHN, GH-N, Growth Hormone, Growth hormone 1, hGH-N, Pituitary growth hormone, Somatotropin, GRH3002-10ug, GRH3002-20ug, GRH3002-50ug, GRH3002-100ug, GRH3002-250ug, GRH3002-500ug, GRH3002-1mg, GRH3002-010, GRH3002-020, GRH3002-050, GRH3002-100, GRH3002-250, GRH3002-500, GRH3002-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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