Comparison

Recombinant human Hexokinase 4 protein

Item no. NKM-HXK0702-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MLDDRARMEA AKKEKVEQIL AEFQLQEEDL KKVMRRMQKE MDRGLRLETH EEASVKMLPT YVRSTPEGSE VGDFLSLDLG GTNFRVMLVK VGEGEEGQWS VKTKHQMYSI PEDAMTGTAE MLFDYISECI SDFLDKHQMK HKKLPLGFTF SFPVRHEDID KGILLNWTKG FKASGAEGNN VVGLLRDAIK RRGDFEMDVV AMVNDTVATM IS
Citations Jon E. et al.,(2003) J.Exp Biology. 206: 2049-2057
NCBI NP_000153
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GCK,glucokinase,MODY2,Maturity onset diabetes of the young 2,Hexokinase 4,HK4,Hexokinase type IV,HK IV,Hexokinase-D
Similar products GCK, GK, Glucokinase, Hexokinase type IV, Hexokinase-4, Hexokinase-D, GLK, HHF3, HK4, HXKP, ATP D hexose 6 phosphotransferase, Glucokinase isoform 1, Hexokinase 4, Hexokinase D, Hexokinase D pancreatic isozyme, Hexokinase4, HexokinaseD, HHF 3, HK 4, HK IV, Maturity onset diabetes of the young 2, MODY 2, MODY2., EC 2.7.1.2, HXK0702-10ug, HXK0702-20ug, HXK0702-50ug, HXK0702-100ug, HXK0702-250ug, HXK0702-500ug, HXK0702-1mg, HXK0702-10, HXK0702-20, HXK0702-50, HXK0702-100, HXK0702-250, HXK0702-500, HXK0702-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.3 kDa (485aa)
Description
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase4 is found in the liver and pancreatic beta-cells, where it is controlled by insulin (activation) and glucagon (inhibition). In pancreatic beta-cells, type IV enzyme acts as a glucose sensor to modify insulin secretion. Hexokinase4 is commonly called glucokinase. Recombinant human Hexokinase4, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-465aa
Species of Protein
Human
Manufacturer - Search Terms
Glucokinase, GCK, GCK, Hexokinase 4, EC 2.7.1.2, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D, Glucokinase, ATP D hexose 6 phosphotransferase, GK, GLK, Glucokinase, Glucokinase isoform 1, Hexokinase 4, Hexokinase D, Hexokinase D pancreatic isozyme, Hexokinase4, HexokinaseD, HHF 3, HHF3, HK 4, HXKP, Maturity onset diabetes of the young 2, MODY 2, MODY2., HXK0702-10ug, HXK0702-20ug, HXK0702-50ug, HXK0702-100ug, HXK0702-250ug, HXK0702-500ug, HXK0702-1mg, HXK0702-10, HXK0702-20, HXK0702-50, HXK0702-100, HXK0702-250, HXK0702-500, HXK0702-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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