Comparison

Recombinant human Hexokinase 1 protein

Item no. NKM-HXK0704-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MIAAQLLAYY FTELKDDQVK KIDKYLYAMR LSDETLIDIM TRFRKEMKNG LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVHMESE VYDTPENIVH GSGSQLFDHV AECLGDFMEK RKIKDKKLPV GFTFSFPCQQ SKIDEAILIT WTKRFKASGV EGADVVKLLN KAIKKRGDYD ANIVAVVNDT
Citations Jon E. et al.,(2003) J.Exp Biology. 206 : 2049-2057.
Furuta H. et al.,(1996) Genomics. 36(1):206-9.

Tsumura Y, et al. TMG-123, a novel glucokinase activator, exerts durable effects on hyperglycemia without increasing triglyceride in diabetic animal models. (PLoS One. 2017){https://pubmed.ncbi.nlm.nih.gov/28207836/}
Yoshitake T, et al. Anti-Hexokinase 1 Antibody as a Novel Serum Biomarker of a Subgroup of Diabetic Macular Edema. (Sci Rep. 2019){https://pubmed.ncbi.nlm.nih.gov/30886155/}
NCBI NP_000179.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HK1,Hexokinase 1,EC 2.7.1.1,Hexokinase type I,HK I,Brain form hexokinase,Hexokinase-1,BB404130,dea,Glycolytic enzyme,HEXOKIN,Hexokinase PI,Hexokinase type I,Hexokinase,tumor isozyme,Hexokinase-A,HK1 tb,Hk1-s,HK1-ta,HK1-tc,HKI,HXK1,mHk1-s.
Similar products Hexokinase1, HXK0704-10ug, HXK0704-20ug, HXK0704-50ug, HXK0704-100ug, HXK0704-250ug, HXK0704-500ug, HXK0704-1mg, HXK0704-10, HXK0704-20, HXK0704-50, HXK0704-100, HXK0704-250, HXK0704-500, HXK0704-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
104.6 kDa (937aa)
Description
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase1 is found in the adipose tissue and liver and encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this hexokinase1 have been associated with hemolytic anemia due to hexokinase deficiency. Recombinant human Hexokinase1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-917aa
Bioactivity Comment Only
Specific activity is > 8, 000pmol/min/ug. One unit will convert 1pmole of D-Glucose to D-Glucose-6-phosphate per minute at pH 7.5 at 37C.
Species of Protein
Human
Manufacturer - Search Terms
Hexokinase1, HXK0704-10ug, HXK0704-20ug, HXK0704-50ug, HXK0704-100ug, HXK0704-250ug, HXK0704-500ug, HXK0704-1mg, HXK0704-10, HXK0704-20, HXK0704-50, HXK0704-100, HXK0704-250, HXK0704-500, HXK0704-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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