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Recombinant human IL-1 beta/IL1B protein

Recombinant human IL-1 beta/IL1B protein

Item no.	NKM-ILB0701-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
Citations	Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629. Michaud DS., et al. (2006), Cancer Res.66(8):4525-30 Choi DY, et al. Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1β. (Biosens Bioelectron. 2022){https://pubmed.ncbi.nlm.nih.gov/35144170/} Park RW, et al. Mobile Point-of-Care Device Using Molecularly Imprinted Polymer-Based Chemosensors Targeting Interleukin-1β Biomarker. (Biosensors. 2023){https://pubmed.ncbi.nlm.nih.gov/38131773/}
NCBI	NP_000567.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-1 beta,IL-1 beta,Catabolin,IL1F2
Similar products	IL1F2, IL1 b, ILB0701-10ug, ILB0701-20ug, ILB0701-50ug, ILB0701-100ug, ILB0701-250ug, ILB0701-500ug, ILB0701-1mg, ILB0701-10, ILB0701-20, ILB0701-50, ILB0701-100, ILB0701-250, ILB0701-500, ILB0701-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	17 kDa (154aa) confirmed by MALDI-TOF
Description	Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant human IL-1beta was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species	Human
Gene Category	Hormones & Cytokines
Domain	117-269aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 12pg/ml.
Species of Protein	Human
Manufacturer - Search Terms	IL1 b, IL1F2, ILB0701-10ug, ILB0701-20ug, ILB0701-50ug, ILB0701-100ug, ILB0701-250ug, ILB0701-500ug, ILB0701-1mg, ILB0701-10, ILB0701-20, ILB0701-50, ILB0701-100, ILB0701-250, ILB0701-500, ILB0701-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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NKM-ILB0701-100ug-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 7/31/2025

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