Comparison

Recombinant human IL-4 protein

Item no. NKM-ILD0905-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Citations Van Kimmenade A., et al. (1988) Eur J Biochem. 173(1):109-14.
Yokota T., et al. (1986) Proc. Natl. Acad. Sci. uSA. 83(16):5894-8.

Lee HM, et al. A comparative study of the effects of inhibitory cytokines on human natural killer cells and the mechanistic features of transforming growth factor-beta. (Cell Immunol. 2014){https://pubmed.ncbi.nlm.nih.gov/24879062/}
NCBI NP_000580
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Pitrakinra,MGC79402,Lymphocyte stimulatory factor 1,Interleukin-4 isoform 1,Interleukin 4,IL-4,BSF1,Binetrakin,BCGF1,B-cell stimulatory factor 1,B-cell growth factor 1,BCDF
Similar products IL-4, IL4, Interleukin-4, Interleukin 4, IL 4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra, B-cell growth factor 1, BCGF-1, BCGF1, BSF1, MGC79402, B cell growth factor 1, BCGF 1, BSF 1, Interleukin4, B cell stimulatory factor 1, BCDF, Pitrakinara, Interleukin-4 isoform 1, Interleukin 4 isoform 1, ILD0905-10ug, ILD0905-20ug, ILD0905-50ug, ILD0905-100ug, ILD0905-250ug, ILD0905-500ug, ILD0905-1mg, ILD0905-010, ILD0905-020, ILD0905-050, ILD0905-100, ILD0905-250, ILD0905-500, ILD0905-01M
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17.2 kDa (150aa) confirmed by MALDI-TOF
Description
Interleukin-4 (IL-4) is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. Interleukin-4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant Interleukin-4 protein, fused to His-tag at N-terminus, was expressed in E. coli and was purified by conventional chromatography techniques, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
25-153aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
The ED50 for this effect is less or equal to 0.5ng/ml. Measured in a cell proliferation assay using TF1 human erythroleukemic cells.
Species of Protein
Human
Manufacturer - Search Terms
Pitrakinra, Pitrakinara, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin-4, Interleukin4, Interleukin 4 isoform 1, Interleukin 4, IL-4, IL4, IL 4, BSF-1, BSF1, BSF 1, Binetrakin, BCGF-1, BCGF1, BCGF 1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF, B cell stimulatory factor 1, B cell growth factor 1, ILD0905-10ug, ILD0905-20ug, ILD0905-50ug, ILD0905-100ug, ILD0905-250ug, ILD0905-500ug, ILD0905-1mg, ILD0905-010, ILD0905-020, ILD0905-050, ILD0905-100, ILD0905-250, ILD0905-500, ILD0905-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
available

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