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Recombinant mouse Leptin/OB protein

Recombinant mouse Leptin/OB protein

Item no.	NKM-LEP0701-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Obesity Endocrine Regulation of Lipid Metabolism
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
Citations	Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7), 3027-32. Anini Y., et al. (2003) Diabetes. 52(2), 252-259. Hyogo H., et al. (2002) J. Biol. Chem. 277(37), 34117-34124.
NCBI	NP_032519
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LEP,OB,OBS,Leptin Mouse,Obesity factor,Obese protein,Leptin
Similar products	Leptin, LEP, OB, OBS, Obese protein, Obesity factor, Leptin Mouse, LEP0701-10ug, LEP0701-20ug, LEP0701-50ug, LEP0701-100ug, LEP0701-250ug, LEP0701-500ug, LEP0701-1mg, LEP0701-10, LEP0701-20, LEP0701-50, LEP0701-100, LEP0701-250, LEP0701-500, LEP0701-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	16 kDa (147aa) confirmed by MALDI-TOF
Description	Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species	Mouse
Gene Category	Hormones & Cytokines
Domain	22-167aa
Species of Protein	Mouse
Manufacturer - Search Terms	Leptin, OB, LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin, LEP0701-10ug, LEP0701-20ug, LEP0701-50ug, LEP0701-100ug, LEP0701-250ug, LEP0701-500ug, LEP0701-1mg, LEP0701-10, LEP0701-20, LEP0701-50, LEP0701-100, LEP0701-250, LEP0701-500, LEP0701-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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