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Recombinant human PP2C alpha/PPM1A protein

Recombinant human PP2C alpha/PPM1A protein

Item no.	NKM-PPC3001-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Metabolism Glucose Homeostasis Targets for Rodent Neurosciences Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins Obesity SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWIL>MGAF LDKPKMEKHN AQGQGNGLRY GLSSMQGWRV EMEDAHTAVI GLPSGLESWS FFAVYDGHAG SQVAKYCCEH LLDHITNNQD FKGSAGAPSV ENVKNGIRTG FLEIDEHMRV MSEKKHGADR SGSTAVGVLI SPQHTYFINC GDSRGLLCRN RKVHFFTQDH KPSNPLEKER IQNAGGSVMI QRVNGSLAVS
Citations	Das, A. K. et al. (1996) EMBO J. 15, 6798-6809
NCBI	NP_066283
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Pyruvate dehydrogenase phosphatase catalytic subunit 1,Pyruvate dehydrogenase acetyl-transferring-phosphatase 1,Protein phosphatase Mg2+/Mn2+dependent 1A,Protein phosphatase 2C,Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform,Protein phosphatase 1A (formerly 2C),PPM2C,PPM1A,PP2CA,PP2C alpha,PDPC 1,PDP 1,PDP,MGC9201,FLJ42306,EC 3.1.3.43
Similar products	PPM1A, PDP1, PDP, PPM2C, Protein phosphatase 2C, Pyruvate dehydrogenase phosphatase catalytic subunit 1, PP2CA, FLJ42306, MGC9201, PP2Calpha, PP2C alpha, PP2C-alpha, PDP 1, PDPC 1, Pyruvate dehydrogenase acetyl-transferring-phosphatase 1, Protein phosphatase Mg2+/Mn2+dependent 1A, Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform, Protein phosphatase 1A (formerly 2C), PP2C A, EC 3.1.3.43, PPC3001-10ug, PPC3001-20ug, PPC3001-50ug, PPC3001-100ug, PPC3001-250ug, PPC3001-500ug, PPC3001-1mg, PPC3001-010, PPC3001-020, PPC3001-050, PPC3001-100, PPC3001-250, PPC3001-500, PPC3001-01M
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Enzyme Activity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	46.6 kDa (418aa) confirmed by MALDI-TOF
Description	Protein phosphatase 2C (PP2C alpha) is a Mn2+- or Mg2+- dependent protein serine/threonine phosphatase that is essential for regulating cellular stress response in eukaryotes. The protein coding region of PP2C alpha (amino acids 1-382) was cloned into an E. coli expression vector. PP2C alpha was overexpressed in E. coli as a soluble His-tag fusion protein, and it was purified by conventional column chromatographic techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 10mM Tris-HCl buffer (pH 7.5) containing 50mM NaCl, 2mM DTT, 1mM MnCl2, 20%glycerol
Antigen Species	Human
Gene Category	Signal Transduction
Domain	1-382aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Specific activity is > 1, 400unit/mg, and is defined as the amount of enzyme that hydrolyze 1.0nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C.
Species of Protein	Human
Manufacturer - Search Terms	Pyruvate dehydrogenase phosphatase catalytic subunit 1, Pyruvate dehydrogenase acetyl-transferring-phosphatase 1, Protein phosphatase Mg2+/Mn2+dependent 1A, Protein phosphatase 2C, Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform, Protein phosphatase 1A (formerly 2C), PPM2C, PPM1A, PP2C-alpha, PP2Calpha, PP2CA, PP2C A, PP2C alpha, PDPC 1, PDP1, PDP 1, PDP, MGC9201, FLJ42306, EC 3.1.3.43, PPC3001-10ug, PPC3001-20ug, PPC3001-50ug, PPC3001-100ug, PPC3001-250ug, PPC3001-500ug, PPC3001-1mg, PPC3001-010, PPC3001-020, PPC3001-050, PPC3001-100, PPC3001-250, PPC3001-500, PPC3001-01M
Manufacturer - Alternative Names	Pyruvate dehydrogenase phosphatase catalytic subunit 1, Pyruvate dehydrogenase acetyl-transferring-phosphatase 1, Protein phosphatase Mg2+/Mn2+dependent 1A, Protein phosphatase 2C, Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform, Protein phosphatase 1A (formerly 2C), PPM2C, PPM1A, PP2CA, PP2C alpha, PDPC 1, PDP 1, PDP, MGC9201, FLJ42306, EC 3.1.3.43

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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