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Recombinant human Sirtulin 6/SIRT6 protein

Recombinant human Sirtulin 6/SIRT6 protein

Item no.	NKM-SIR0901-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Metabolism Diabetes By Cell Type Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS
Citations	Michishita E., et al. (2008) Nature. 452(7186):492-6. Mostoslavsky R., et al. (2006) Cell. 124(2):315-29.
NCBI	NP_057623
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NAD-dependent protein deacylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6,SIR2-like protein 6,SIR2L6
Available
Manufacturer - Type	Proteins
Manufacturer - Category	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	41 kDa (375aa) confirmed by MALDI-TOF
Description	The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 0.1mM PMSF
Antigen Species	Human
Gene Category	Cell Cycle
Domain	1-355aa
Species of Protein	Human
Manufacturer - Search Terms	Mono-ADP-ribosyltransferase sirtuin-6, NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2 like protein 6, SIR2 related protein type 6, SIR2L6, SIR2-like protein 6, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, Sirtuin type 6, Sirtuin6, SIR0901-10ug, SIR0901-20ug, SIR0901-50ug, SIR0901-100ug, SIR0901-250ug, SIR0901-500ug, SIR0901-1mg, SIR0901-010, SIR0901-020, SIR0901-050, SIR0901-100, SIR0901-250, SIR0901-500, SIR0901-01M
Manufacturer - Similar Names	Mono-ADP-ribosyltransferase sirtuin-6, NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2 like protein 6, SIR2 related protein type 6, SIR2L6, SIR2-like protein 6, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, Sirtuin type 6, Sirtuin6, SIR0901-10ug, SIR0901-20ug, SIR0901-50ug, SIR0901-100ug, SIR0901-250ug, SIR0901-500ug, SIR0901-1mg, SIR0901-010, SIR0901-020, SIR0901-050, SIR0901-100, SIR0901-250, SIR0901-500, SIR0901-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 12/4/2025

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