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Recombinant human SMAC/Diablo protein

Recombinant human SMAC/Diablo protein

Item no.	NKM-SMA0801-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis SDS-PAGE By Organ Breast Cancer
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	T7 Epitope
Purity	> 95% by SDS-PAGE
Sequence	MASMTGGQQM GRGSMAVPIA QKSEPHSLSS EALMRRAVSL VTDSTSTFLS QTTYALIEAI TEYTKAVYTL TSLYRQYTSL LGKMNSEEED EVWQVIIGAR AEMTSKHQEY LKLETTWMTA VGLSEMAAEA AYQTGADQAS ITARNHIQLV KLQVEEVHQL SRKAETKLAE AQIEELRQKT QEEGEERAES EQEAYLRED
Citations	Srinivasula SM., et al. (2000). J Biol Chem. 275(46):36152-7. Du C., et al. (2000). Cell. 102(1):33-42.
NCBI	NP_063940
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Diablo isoform 1,SMAC3,DIABLO-S,FLJ10537,FLJ25049,Diablo isoform 1,SMAC/Diablo,Diablo isoform 1 0610041G12Rik,DBOH,Diablo homolog,DIABLO S,Diablo homolog (Drosophila),Mitochondrial Smac protein,Diablo homolog mitochondrial,SMAC 3,Smac protein,Direct IAP binding protein with low pI,Second mitochondria derived activator of caspase.
Similar products	DIABLO-S, FLJ10537, FLJ25049, SMAC3, Diablo homolog, Mitochondrial Smac protein, DBOH, Diablo homolog (Drosophila), Diablo homolog mitochondrial, DIABLO S, Direct IAP binding protein with low pI, SMAC 3, Smac protein, SMADiablo, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, Second mitochondria derived activator of caspase., SMA0801-10ug, SMA0801-20ug, SMA0801-50ug, SMA0801-100ug, SMA0801-250ug, SMA0801-500ug, SMA0801-1mg, SMA0801-10, SMA0801-20, SMA0801-50, SMA0801-100, SMA0801-250, SMA0801-500, SMA0801-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	22 kDa (199aa) confirmed by MALDI-TOF
Description	Smac/Diablo is one of the proapoptotic proteins. Smac promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. Recombinant human Smac fused to T7-tag. at N-terminus was expressed in E. coli and purified by conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5)
Antigen Species	Human
Gene Category	Cancer
Domain	56-239aa
Species of Protein	Human
Manufacturer - Search Terms	SMADiablo, Diablo isoform 1, SMAC3, DIABLO-S, FLJ10537, FLJ25049, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, DBOH, Diablo homolog, DIABLO S, Diablo homolog (Drosophila), Mitochondrial Smac protein, Diablo homolog mitochondrial, SMAC 3, Smac protein, Direct IAP binding protein with low pI, Second mitochondria derived activator of caspase., SMA0801-10ug, SMA0801-20ug, SMA0801-50ug, SMA0801-100ug, SMA0801-250ug, SMA0801-500ug, SMA0801-1mg, SMA0801-10, SMA0801-20, SMA0801-50, SMA0801-100, SMA0801-250, SMA0801-500, SMA0801-1
Manufacturer - Alternative Names	Diablo isoform 1, SMAC3, DIABLO-S, FLJ10537, FLJ25049, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, DBOH, Diablo homolog, DIABLO S, Diablo homolog (Drosophila), Mitochondrial Smac protein, Diablo homolog mitochondrial, SMAC 3, Smac protein, Direct IAP binding protein with low pI, Second mitochondria derived activator of caspase.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/4/2025

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