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Recombinant human Smad4 protein

Recombinant human Smad4 protein

Item no.	NKM-SMD0901-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Adenocarcinoma SDS-PAGE By Organ Colorectal Cancer
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK KDELDSLITA ITTNGAHPSK CVTIQRTLDG RLQVAGRKGF PHVIYARLWR WPDLHKNELK HVKYCQYAFD LKCDSVCVNP YHYERVVSPG IDLSGLTLQS NAPSSMMVKD EYVHDFEGQP SLSTEGHSIQ TIQHPPSNRA STETYSTPAL LAPSESNATS TA
Citations	Shi Y., et al. (1997) Nature. 388(6637):87-93. de Caestecker MP, et al. (1997) J Biol Chem. 272(21):13690-6.
NCBI	NP_005350
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4.
Similar products	SMAD4, Smad4, DPC4, JIP, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, hSMAD4, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	62.6 kDa (572aa)
Description	SMAD4 belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription and may also act as a tumor suppressor. Recombinant SMAD4 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
Antigen Species	Human
Gene Category	Cancer
Domain	1-552aa
Species of Protein	Human
Manufacturer - Search Terms	Smad4, Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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